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General optimization: Start conservative (10 units) and titrate to the minimum effective dose that produces your desired effects
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A patient with low B12 may also have peripheral neuropathy, small fiber neuropathy, autoimmune disease, spine-related nerve irritation, inflammatory disease, orthopedic pain, or medication-related symptoms
Effect of IGF-1 on protein metabolism in burned rats [PMID: 10483905] Laboratory literature summary: Effect of IGF-1 on protein metabolism in burned rats
Downregulations in gene-expression profiles of ETC complexes I, IV and V was also reported in the postmortem frontal cortex of people with BD compared to control samples without BD [47]
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